Lizzie begins to sit for some of the most celebrated members of the Pre-Raphaelite Brotherhood, posing for John Everett Millais as Shakespeare's Ophelia, for William Holman Hunt--and especially for Rossetti, who immortalizes her in countless paintings as his namesake's beloved Beatrice. The passionate visions Rossetti creates on canvas are echoed in their intense affair. But while Lizzie strives to establish herself as a painter and poet in her own right, betrayal, illness, and addiction leave her struggling to save her marriage and her sense of self.